deamidation: ph、Deamination、Deamidation在PTT/mobile01評價與討論，在ptt社群跟網路上大家這樣說
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deamidation: ph在Asparagine Deamidation Dependence on Buffer Type, pH ...的討論與評價
由 AL Pace 著作 · 2013 · 被引用 123 次 — A study of the deamidation rate as a function of pH was conducted at 40°C using 5 mg/mL mAb1 in 20 mM acetate buffered solution in the pH range of 5.3-8.3.
deamidation: ph在Deamidation - Wikipedia的討論與評價
In general, deamidation can be eliminated by proteolysis at an acidic pH or at a slightly basic pH (4.5 and 8.0, respectively) using the endoprotease, ...
deamidation: ph在Asparagine deamidation dependence on buffer ... - PubMed的討論與評價
由 AL Pace 著作 · 2013 · 被引用 123 次 — The deamidation of asparagine into aspartate and isoaspartate moieties is a major pathway for the chemical degradation of monoclonal antibodies (mAbs).
deamidation: ph在ptt上的文章推薦目錄
deamidation: ph在Protein Formulation and Delivery - Google 圖書結果的討論與評價
In deamidation reactions of short chain peptides uncomplicated by structural alterations or covalent dimerization (20), the pH-rate profiles exhibit the ...
deamidation: ph在Deamidation and isomerization liability analysis of 131 clinical ...的討論與評價
Figure 1. Deamidation and isomerization mechanism. The dominant deamidation pathway at pH 8.5 is Asu-mediated (Asn → Asu ⇌ [IsoAsp ⇌ Asp]).
deamidation: ph在Asparagine Deamidation: pH-Dependent ... - ResearchGate的討論與評價
At low pH, the calculations show that deamidation occurs by direct acid-catalyzed hydrolysis to aspartate. At neutral to basic pH, deamidation proceeds by the ...
deamidation: ph在Characterization and Monitoring of pH Induced Deamidation ...的討論與評價
Characterization and Monitoring of pH Induced Deamidation. Using Benchtop X500B and BioPharmaView™ Software. Luo JI1; Sibylle Heidelberger 2; Annu Uppal3.
deamidation: ph在Effects of amino acid sequence, buffers, and ionic strength on ...的討論與評價
deamidation pathway at neutral and alkaline pH val- ues. The rates of deamidation of Asn residues in the peptides studied were not affected ...
deamidation: ph在Deamidation of Proteins and Peptides: Monograph 0001的討論與評價
Neutral pH (Beta-aspartyl shift mechanism). The non-enzymatic modification of asparagine and aspartate residues at physiological pH occurs ...
deamidation: ph在Divining Deamidation and Isomerization in Therapeutic Proteins的討論與評價
Deamidation of an ASN residue has been experimentally well characterized.[21-23] Among the multiple pathways that are feasible, pH-dependent ...