Glutamine pka、Deamination、Deamidation在PTT/mobile01評價與討論，在ptt社群跟網路上大家這樣說
Glutamine pka關鍵字相關的推薦文章
Glutamine pka在Asparagine Deamidation Dependence on Buffer Type, pH ...的討論與評價
由 AL Pace 著作 · 2013 · 被引用 123 次 — A study of the deamidation rate as a function of pH was conducted at 40°C using 5 mg/mL mAb1 in 20 mM acetate buffered solution in the pH range of 5.3-8.3.
Glutamine pka在Deamidation - Wikipedia的討論與評價
In general, deamidation can be eliminated by proteolysis at an acidic pH or at a slightly basic pH (4.5 and 8.0, respectively) using the endoprotease, ...
Glutamine pka在Asparagine deamidation dependence on buffer ... - PubMed的討論與評價
由 AL Pace 著作 · 2013 · 被引用 123 次 — The deamidation of asparagine into aspartate and isoaspartate moieties is a major pathway for the chemical degradation of monoclonal antibodies (mAbs).
Glutamine pka在ptt上的文章推薦目錄
Glutamine pka在Protein Formulation and Delivery - Google 圖書結果的討論與評價
In deamidation reactions of short chain peptides uncomplicated by structural alterations or covalent dimerization (20), the pH-rate profiles exhibit the ...
Glutamine pka在Deamidation and isomerization liability analysis of 131 clinical ...的討論與評價
Figure 1. Deamidation and isomerization mechanism. The dominant deamidation pathway at pH 8.5 is Asu-mediated (Asn → Asu ⇌ [IsoAsp ⇌ Asp]).
Glutamine pka在Asparagine Deamidation: pH-Dependent ... - ResearchGate的討論與評價
At low pH, the calculations show that deamidation occurs by direct acid-catalyzed hydrolysis to aspartate. At neutral to basic pH, deamidation proceeds by the ...
Glutamine pka在Characterization and Monitoring of pH Induced Deamidation ...的討論與評價
Characterization and Monitoring of pH Induced Deamidation. Using Benchtop X500B and BioPharmaView™ Software. Luo JI1; Sibylle Heidelberger 2; Annu Uppal3.
Glutamine pka在Effects of amino acid sequence, buffers, and ionic strength on ...的討論與評價
deamidation pathway at neutral and alkaline pH val- ues. The rates of deamidation of Asn residues in the peptides studied were not affected ...
Glutamine pka在Deamidation of Proteins and Peptides: Monograph 0001的討論與評價
Neutral pH (Beta-aspartyl shift mechanism). The non-enzymatic modification of asparagine and aspartate residues at physiological pH occurs ...
Glutamine pka在Divining Deamidation and Isomerization in Therapeutic Proteins的討論與評價
Deamidation of an ASN residue has been experimentally well characterized.[21-23] Among the multiple pathways that are feasible, pH-dependent ...